This paper proposes a variable sampling interval multivariate T² control chart with sampling at fixed times, where samples are taken at specified equally spaced fixed time points and additional samples are allowed between these fixed times when indicated by the preceding T² statistics. At fixed sampling points, the T² statistics are composed of all quality characteristics and a part of quality characteristics are selected to obtain T² statistics at additional sampling points. A Markov chain approach is used to evaluate the performance of the proposed chart. Numerical studies for the performance of the proposed chart show that the proposed chart reduces the observations obtained from a process and detects the assignable cause of a process with low correlated quality characteristics quickly.