Nowadays, customer-oriented manufacturing enterprises such as airplane, ship, ship engine, etc are knowledge-intensive and higher added value industries. In these companies, to quickly respond customer's order, a quotation management is a very important task. But, this task is very complex, time-consuming, resource- consuming, and difficult process because it is related with many departments within a company. In this paper, for the effective and efficient quotation management, the concept of product specification framework is introduced because a quotation BOM (bills of material) can be created from product specification. Also, this paper presents the product specification framework based quotation management process and implements the quotation management system for the ship engine division of 'H' company, one of customer-oriented manufacturing enterprises. As a result, the proposed quotation management concept reduced a lead time of drawing out quotations from 3~10 days to 1 hour. And, the constructed quotation management system achieved a rapidity, accuracy, quality, and workload reduction of the quotation management process.