Since ISO 9001 quality system was established in 1987, many companies have adopted it for assuring the quality of their processes. Not only manufacturing companies but service industries such as hospitals, armies, educational institutes, banks are now implementing ISO 9001 quality management system. In this study, we proposed the definitions of customers, manufacturing processes, products, and quality characteristics of the ISO 9001:2000(E) quality management system in university. An implementation procedure of ISO 9001:2000(E) quality management system in university was also suggested. Furthermore, we dealt with the case study of 'C' College's ISO 9001:2000(E) quality management system and showed some of its effects