In the plastic extrusion process, product quality is influenced by work condition for temperature of cylinders and dies. The work conditions are various, so it is difficult to standardization of the work conditions. Therefore, the work conditions are depended on the workers of experience and skill. In the plastic extrusion process, it has five control heating points on the cylinder and three control heating points on the die. In addition, there is one control point on the extrusion process. It is extrusion speed. In this case, we don't know how these affect product quality. We structure the multiple linear regression equation with the temperature of cylinders and dies as independent variables and the product weight as dependent variable. We solve this equation using statistic computer package named Juse-Qcas.